Tuesday, February 7, 2023

A simple test could detect Alzheimer’s early through the blood

Preliminary diagnostic tests, blood tests or brain imaging studies. Diagnose Alzheimer’s When the first signs have not yet appeared, this is something that scientists have been trying to solve for a long time. Most of the times in which the disease is confirmed, the brain damage It has wreaked its first havoc.

A group of neuroscientists has developed a test capable of detecting The specific biomarker of this pathology is called “brain-derived tau” (or BD-tau). through blood sampling. study, published by the journal mindhave reported that this biomarker outperformed the results of tests that were available to date for the diagnosis of Alzheimer’s.

“now-a-days, Neuroimaging tests are necessary to diagnose Alzheimer’s disease.“, explained Dr. Thomas Karikari of the University of Pittsburgh. “These tests are expensive, they take a long time to schedule, and many patients do not have access Magnetic resonance imaging and positron emission tomography or PET scan.

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On the other hand, the methods so far detect alzheimer’s through blood Able to detect pathological abnormalities. However, in many cases they are located Markers of neurodegeneration characteristic of other diseasesNot being able to give a very accurate diagnosis.

In short, using current techniques can provide clues about presence of a neurodegenerative disease, but it does not specifically detect Alzheimer’s. That’s why this new discovery is so important. And this promises the possibility of effective diagnosis of this disorder.

Scientists participating in the study designed a antibody that binds to BD-tau, This makes it easy to detect it in the blood. tested in Over 600 patient samples from 5 cohorts independent. These include patients in whom Alzheimer’s was diagnosed after death, or patients with memory loss.

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tests conducted showed that the levels of Bd-tau detected in blood samples from Alzheimer’s patients were able to Differentiate the disease from other neurodegenerative disorders, Now the scientists want to expand the spectrum of patients who have not been included in the research.

“There is a great need for diversity in clinical research, not only because of skin color, but also because of socioeconomic status,” Karikari said.

The next study that this group of scientists set out to include participants of different races, Adults Not Showing Signs of Alzheimer’s And people who are in different stages of the disease. In this way, being able to diagnose a greater number of antibodies can be applied to a greater population.

Nation World News Desk
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