Monday, December 05, 2022

Amoxicillin, a common antibiotic used to treat infections in children, is in short supply in the US.

three out of four main manufacturers The antibiotic amoxicillin, commonly used to treat bacterial infections in children, has reported supply limits in the United States.

Hikma Pharmaceuticals plc and Teva Pharmaceutical Industries Ltd. reported limited supplies of various doses of the drug to the University of Utah Drug Information Service, which tracks drug shortages. Sandoz, a division of Novartis AG and one of the world’s largest generic drug manufacturers, faces supply constraints in the United States as well as other countries. Demand A “critical” part of the common antibiotic, a spokesman said.

Amoxicillin can be prescribed for many things, including ear and throat infections, and it comes in many forms. According to the drug tracker at the University of Utah, children usually take the liquid form of the drug, which is where most shortages occur.

Sandoz spokeswoman Leslie Pott said: “The rapid succession of the effects of the pandemic and the resulting swings in demand, lack of manufacturing capacity, raw material shortages and the ongoing energy crisis mean that we face an exceptionally difficult situation in the near term.” are doing.”

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According to spokesman Steve Weiss, Hickama has all of its oral amoxicillin products “on assignment.” This means that the company is limiting new orders to ensure that it meets existing obligations.

“Our number one priority is to honor our commitments to our existing customers, and the assignment allows us to do that,” Weiss said. He said the company is currently fulfilling all of its orders domestically and has “sufficient” supplies for its existing contracts.

Teva did not respond to a request for comment.

“Less Effective” Option
The US Food and Drug Administration said it is aware of “intermittent supply disruptions” of amoxicillin products in the United States and is working with manufacturers to correct the problem. In addition to supply problems in the United States, Canada and Australia have also reported amoxicillin shortages.

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According to the Centers for Disease Control and Prevention, patients who are not receiving the drug may use other antibiotics instead, but amoxicillin is the preferred initial treatment for many common pediatric infections.

“Imaginatively, if amoxicillin doesn’t come in stock for some time, we’ll have to use less effective antibiotics with potentially more side effects,” said Sean Gallagher, MD, a pediatrician in Newark, Ohio. He said there was a shortage of medicine in nearby CVS locations, but all his patients were able to find medicine in other pharmacies.

CVS Health Corp., one of the largest drug chains in the United States with more than 9,900 retail stores, said in a statement that some stores are experiencing shortages of certain doses of the drug. Walgreens Boots Alliance Inc. did not respond to a request for comment.

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