Outpatient antibiotic treatment allows many appendicitis patients to avoid surgery and hospitalization, according to a study by researchers University of California at Los Angeles.
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The study involved 726 participants with image-confirming appendicitis who were randomly assigned to receive antibiotics at 25 different hospitals from May 1, 2016 to February 28, 2020.
46% of them were discharged from the emergency department within 24 hours. Therefore, this outpatient treatment was associated with less than one serious adverse event per 100 patients in the week following discharge.
Too, Outpatient treatment was shown to be safe in a wide range of very diverse patients and demonstrated 90% of patients treated with antibiotics in all study centers. Unlike hospitalization, outpatient treatment does not produce subsequent multiple appendectomies, but a faster recovery. According to statistics, patients missed out on fewer days of work due to their quick recovery.
This study is an ongoing analysis of the results of the comparison of antibiotics and appendectomy (CODA) trial results, which found that antibiotic treatment was non-inferior to emergency appendectomy. After the trial, the American College of Surgeons said high-quality evidence indicated that most patients could be treated with antibiotics.
According to one of the study’s investigators: “Outpatient management of appendicitis is safe for many people and can reduce the use and cost of medical care,” the researchers summarized in their article published in the scientific journal. ‘Jama Network Open’.
