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Friday, October 07, 2022

Baby’s metabolism depends on healthy diet during breastfeeding

a Healthy Diet During the lactation period it manages to normalize the lipid content (concentrations of various types of fats) in the mother’s milk and prevent metabolic changes in the offspring. This is confirmed by a recent study conducted by a team from the Obesity and Nutrition Area of ​​the Online Biomedical Research Center (Cyberoban) of the University of the Balearic Islands (UIB) and the Institute of Health Research of the Islands of the Balearic. Islands (Idisba), in collaboration with the Institute of Physiology of the Czech Academy of Sciences. The results have been published in the journal Molecular Nutrition and Food Research,

Through this study, we sought to evaluate, in an animal model, whether normalizing maternal diet during lactation could prevent the harmful effects that an obesogenic diet (which is common in humans) prior to pregnancy and during pregnancy. promotes obesity). Or the lipidomic profile (set of hundreds of lipids) in the milk and plasma of offspring, and it turned out that it is possible to obtain it.

This new knowledge is relevant because, in addition to existing evidence on the importance of the nutritional environment during fetal life for correct development and subsequent health of the offspring, it shows that recovery of a healthy maternal diet during lactation can be prevented. is, at least partly, metabolic disorders in offspring caused by poor diet and obesity during the prenatal stages.

Baby's metabolism depends on healthy diet during breastfeeding

In front of the obesity and nutrition team, Andre Palu and Catalina Pico. Photo: AC/UIB.



chronic pathology

Previous intervention studies in animal models have shown that consumption of an obesogenic diet during the perinatal period affects mammary gland function and, therefore, milk composition, meaning that these changes “program” the offspring for a greater propensity. Can in adulthood to develop chronic pathology. Based on this, the researchers found it interesting to study potential intervention strategies during the lactation period to prevent adverse effects caused by an unbalanced maternal diet during or even before pregnancy. To do this, they analyzed lipidomic profiles to determine changes that may be involved in the risk of developing diseases for offspring at later stages, as well as analysis of plasma profiles of offspring in the late stages of lactation. can also do.

The results of this study showed that maternal consumption of an obesogenic diet during the perinatal period (specifically, one month before pregnancy and during pregnancy and lactation) caused a significant change in the lipid composition of milk and plasma of their babies. causes. preliminary stage. These changes were largely reversed in the milk of mothers who received a balanced diet during lactation and in the plasma of their offspring. Study authors, led by Dr. Catalina Pico, are now studying the extent to which these results (obtained in an animal model) can be extrapolated to humans. In any case, they recommend extreme care in feeding during lactation, as a critical period in which it is possible to correct metabolic changes in the offspring.

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