Tuesday, February 7, 2023

Breast milk from people vaccinated against COVID-19 protects babies

A team of scientists from the University of Florida (UF) Antibodies against virus found in feces of nursing infants of mothers vaccinated against Covid-19 Regarding that infectious disease, a “significant discovery” was revealed this Thursday.

The new study, published in the Journal of Perinatology, builds on another study from the same team published in 2021 that showed The breast milk of a vaccinated person contains antibodies against SARS-CoV-2.Virus that causes Covid-19.

Joseph Larkin III, lead author of the study and professor in the Department of Microbiology and UF Cell Science, said, “Our results suggest the potential transfer of specific antibodies against SARS-CoV-2 through breast milk from a vaccinated mother to the child. “

Scientists analyzed the feces of breastfed babies determined the “presence of antibodies” that had traveled up the intestinal tract of babies

Breast milk of vaccinated women contains antibodies

“When we eat food, it travels through the intestines” and the presence of antibodies in this system “tells” Transfer of antibodies from mother to child,” Although this is an area that “requires further study,” Larkin said.

To arrive at this “significant discovery”, the scientists used a technique called “Deactivation Test” and confirmed that antibodies found in the feces of infants confer protection against the virus.

In laboratory tests, scientists isolated antibodies from the feces of infants and Special lines of cells that have the type of receptors that the SARS-CoV-2 virus uses to penetrate them.

They then introduced a SARS-CoV-2 pseudovirus into the cell, which acts like the virus that causes COVID-19 but It is safe to handle in the laboratory and fluoresces when attached to a cell, So it lights up.

In Larkin’s lab “we found that When antibodies were present there were fewer fluorescent cells than in our controlswhere no antibodies were detected, said co-author Lauren Stafford, a doctoral student in the UF College of Agriculture and Life Sciences (IFAS).

“The antibodies interfere and don’t allow the virus to enter the cells,” Larkin said.

The search for antibodies in the digestive tract involves a valuable findAccording to the study authors, since this virus was often thought to primarily affect the lungs, “but it may also be present in” the organs through which food and liquids pass when swallowed.

“Antibodies taken up through breast milk can provide protective lining in the mouth and gastrointestinal tract of infants”Another co-author of the study, Vivian Valcars Luaces, a specialist in neonatology at UF, explained.

led to the investigation finding that “antibodies in plasma and breast milk of vaccinated women can better neutralize the virus”However, the level of antibodies decreases in six months.

Tracking the path of antibodies, from the moment they are produced in the mother after vaccination until they pass through the baby’s digestive tract, also raises the question of whether these babies actually contracted Covid-19. would be less likely to do so.

A question that would require a “larger study” to answere Previous study was done on 37 mothersSix of them Hispanic, and 25 children, a relatively small number of participants, the researchers noted.

Mother’s milk is the only way to protect children

In the United States, babies under six months of age are not allowed to be vaccinated against COVID-19, so breast milk is the only route that provides immunity to infants.

though Covid-19 antibody levels “decrease” over time in vaccinated individuals“are still higher than pre-vaccine levels,” so the research “supports the idea that a vaccine booster may be needed,” Larkin said.

US Centers for Disease Control and Prevention (CDC) Advise women who are pregnant, lactating or trying to become pregnant to get vaccinated against COVID-19.

According to the CDC, by the end of November 2022, just over 70% of pregnant women in the US had completed the primary series of COVID-19 vaccines, although only 14% had received booster doses.

Nation World News Desk
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