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Can Vitamin D Help Overcome Depression? science and technology

London: A review of 41 global studies suggests that vitamin D supplementation may reduce depressive symptoms in adults with depression.

Depressive symptoms cause a significant disease burden worldwide.

The therapeutic efficacy of current antidepressants is often insufficient, which is why more ways have been discovered to reduce symptoms of depression, for example, from nutritional research.

Vitamin D is believed to regulate the functions of the central nervous system, the disturbances of which have been linked to depression.

Researchers from the University of Eastern Finland analyzed 41 studies from around the world to investigate the efficacy of vitamin D in reducing depressive symptoms in adults by randomized placebo-controlled trials in different populations.

The results, published in the journal Critical Reviews in Food Science and Nutrition, suggest that vitamin D supplementation is more effective than placebo in reducing symptoms of depression in people with depression.

There were large differences in the vitamin D doses used, but vitamin D supplementation was typically 50–100 micrograms per day.

“Despite the wide scope of this meta-analysis, the certainty of the evidence remains low due to the heterogeneity of the population studied and the risk of bias associated with the large number of studies,” said doctoral researcher and lead author Tumas Mikola. of the Institute of Clinical Medicine at the University of Eastern Finland.

“These findings will encourage new, high-level clinical trials in patients with depression to shed more light on the potential role of vitamin D supplementation in the treatment of depression,” Mikola said.

Furthermore, cross-sectional studies have observed an association between depressive symptoms and vitamin D deficiency.

(IANS)

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