Friday, May 27, 2022

CDC Says Fourth COVID-19 Vaccination May Require For Weakened Immunity

The CDC director said Friday that it may be necessary to “update our definition of full vaccination in the future” as more people get boosted. “Right now, we do not have the right to booster vaccinations for all people, at present we have not yet changed the definition of fully vaccinated,” said Dr. Rochelle Walenski during a White House briefing on COVID. The CDC currently states that people are still considered fully vaccinated starting two weeks after the second dose of Moderna or Pfizer vaccines or a single J&J vaccination.



According to updated guidelines from the US Centers for Disease Control and Prevention, people with certain medical conditions that cause them moderate to severe immunodeficiency can get a fourth Covid-19 mRNA shot.

In August, the CDC authorized a third dose for some immunocompromised people ages 18 and older. It said a third dose was needed, not a booster dose (the CDC distinguishes between the two) because the immunocompromised person may not have had a complete immune response from the first two doses.

A study this summer at Johns Hopkins University found that vaccinated immunocompromised people are 485 times more likely to be hospitalized or die from Covid-19 than most vaccinated people. In small studies, fully vaccinated immunocompromised people accounted for about 44% of breakthrough cases requiring hospitalization, according to the CDC. Immunocompromised people are also more likely to transmit the virus to people who have had close contact with them.

The FDA has also authorized booster shots of all three available vaccines for certain people, including immunocompromised ones, the CDC said.

Studies have shown that the booster dose increased the antibody response to the vaccine in some immunocompromised people.

This will allow a fourth shot at least six months after the third dose of mRNA vaccine. The CDC currently has no recommendation for a fourth shot. People should talk to their doctors to determine if this is necessary, the CDC said.

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