Friday, September 30, 2022

Class of blood pressure drugs reduce risk of aneurysms in high blood pressure by 18 percent: Study

taking blood pressure

According to a new study in 20 medical centers, the use of RAAS inhibitors can reduce the chance of brain aneurysm rupture in people with high blood pressure by up to 18%.

An aneurysm is a bulging artery in the brain. When ruptured, the blood can cut off oxygen to the affected area, which can lead to hemorrhagic stroke, coma, and death.

The investigators analyzed data from 2016 to 2021 to evaluate the association of blood pressure medications, including RAAS inhibitors, on the risk of aneurysm rupture.

Among 3,000 patients, 32% of those taking RAAS inhibitors experienced intracranial aneurysm rupture compared with 67% of those using non-RAAS inhibitors. The researchers said they were surprised to find that this finding held true even in patients who had well-controlled high blood pressure.

“Our study highlights that using appropriate antihypertensive medications to achieve normalization of blood pressure can significantly reduce the risk of a ruptured aneurysm,” said Qinghai Huang, MD, PhD, Changhai Hospital, of the Second Military Medical University in Shanghai, China. ,

Based on these data, Huang and colleagues estimated that about 18% of ruptured aneurysms could be prevented if all patients with hypertension and intracranial aneurysms were prescribed with RAAS inhibitors.

Huang concluded, “Given that a third of patients with ruptured aneurysm die and another third remain dependent for activities of daily living, there is a need to identify modifiable risk factors to prevent aneurysm rupture.” Is.”

The study was published in the journal high blood pressure,

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