Friday, January 27, 2023

Coffee may reduce severity of NAFLD in type 2 diabetics

a study of University of Coimbra (Portugal) has revealed that caffeine, polyphenols and other natural products present in coffee may help reduce the severity of non-alcoholic fatty liver disease (NAFLD) in those who are overweight and diabetes type 2 (DMT2).

Nonalcoholic fatty liver is a collective term for liver disorders caused by a build-up of fat in the liver. They can cause liver fibrosis, which can lead to cirrhosis (scarring of the liver) and liver cancer, does not result in NAFLD heavy drinkingBut from unhealthy lifestyle, less exercise and high calorie diet.

Study participants with higher coffee consumption had healthier livers. Those with higher levels of caffeine were less likely to have liver fibrosis, while higher levels of non-caffeinated coffee components were significantly associated with lower IQ scores. fatty liver,

coffee effect

The study, published in the scientific journal Nutrients, suggest that in overweight patients with type 2 diabetes, higher coffee intake is associated with less severe non-alcoholic fatty liver disease. The researchers surveyed 156 borderline obese middle-aged participants about their coffee consumption, 98 of whom had type 2 diabetes, and provided 24-hour urine samples.

They were used to measure caffeine and non-caffeine metabolites, ie the natural products of the breakdown of coffee by the body. This method follows the recent shift towards urinalysis, rather than self-reported consumption, to obtain more defined quantitative data on coffee intake.

decreased caffeine intake is associated with liver fibrosis in NAFLD and other chronic liver diseases. Other components of coffee, including polyphenols, have been suggested to reduce oxidative stress in the liver, reduce the risk of fibrosis, and improve glucose homeostasis in both healthy and overweight subjects. All these factors can also reduce the severity of type 2 diabetes.

Coffee and Diet Changes

due to changes in diet and modern life styleObesity rates are rising and the incidence of both type 2 diabetes and nonalcoholic fatty liver disease is rising, which may eventually become more serious and irreversible conditions, further burdening health care systems.

Our research is the first to show that higher cumulative amounts of caffeine and non-caffeinated metabolites in urine are associated with lower NAFLD severity in overweight people with type 2 diabetes,” said study lead author Dr. John Griffith Jones. Center for Neuroscience and Cell Biologyfrom r University of Coimbra,

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