COVID infection a risk factor for mental health success – study

A study has found that people who have been vaccinated against COVID-19, who have a history of certain mental health conditions, have a higher risk of success infection.

Because vaccines are not 100 percent effective at preventing infection, a “breakthrough infection” occurs when a fully vaccinated person becomes infected and occurs more frequently when the level of virus that is transmitted through the community happens more.

Patients over the age of 65 who had a history of substance abuse, psychotic disorders, bipolar disorder, adjustment disorders, and anxiety had an up to 24 percent increased risk for infection.

Researchers believe that this finding may also be partly due to a poor immune response, due to some of the riskier behaviors associated with certain disorders.

Researchers from the University of California San Francisco and the San Francisco VA Health Care System found that patients with a similar condition in patients younger than 65 had an 11 percent higher risk than those without a mental history.

For both age groups, the data were adjusted for age, sex, race, ethnicity and type of vaccine, as well as smoking and underlying conditions such as obesity, diabetes, sleep apnea, heart, lung, kidney and liver disease, HIV and cancer. it was done.

‘Potential immunity declines more rapidly’

Published in JAMA Network Open, the study tracked data from more than 250,000 US Department of Veterans Affairs patients who had completed their vaccination program against COVID-19.

More than half of patients had received at least one psychiatric diagnosis within the past five years and 14.8 percent developed breakthrough COVID-19 confirmed by a positive test.

Donovan, PhD, of the UCSF Weill Institute for Neurosciences and San Francisco, said: “Our research suggests that increased infections among people with psychiatric disorders are not fully explained by socio-demographic factors or pre-existing conditions. May go.” Francisco VA Health Care System.

“It is possible that immunity decreases more quickly or more strongly for people with mental disorders after vaccination and/or that they may have less protection against new forms”.

The risk was 24 percent higher for those over 65 with substance abuse, 23 percent higher for those with mental disorders, 16 percent higher for bipolar disorder, 14 percent higher for adjustment disorder, and 12 percent higher for anxiety. .

The average age of 263,697 participants was 66 and 90.8 percent were male.

Small Impact for Under-65s

Surprisingly, the study showed significantly less effect in the under-65 group.

Researchers suggest that this may be due to the higher frequency of individualized care for the older group, meaning a higher risk of infection being passed on.

First author Kristen Nishimi, PhD, of the UCSF Weill Institute for Neurosciences and the San Francisco VA Health Care System, said she believes the reduction in rates may be due to the “decreased immune response to the vaccine that is associated with some psychiatric disorders.” which may be more significant in older adults.”

It is also possible that older adults with mental disorders “may require more frequent individualized care, which may increase their interactions with the health care system,” she said.

The same researchers conducted another study earlier this year that found that people with high anxiety and potential post-traumatic stress disorder were more likely to engage in behaviors that put them at risk of COVID-19 infection.


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