COVID Vaccination for Children: Does Increasing the Duration Between Doses Increase Immunity?

lengthen the period between the first and second doses of COVID vaccine in girls and boys can boost your immunity and the risk of side effects, according to an article in the journal Nature,

According to the publication, several studies have shown that people have greater immune protection against COVID after increasing the time between the first and second doses from about eight weeks to four months.

Some parents in Canada and the United States are considering increasing their children’s vaccination intervals on this basis, however, so far no studies or clinical trials its effect has been investigated in infants or young children,

Some scientists think it is best to give infants a timely dose and avoid the risk of infection amid the spread of the BA.5 variant.

“They are delaying the vaccine for a theoretical advantage that could cause real harm to children,” said Jessica Snowden, a pediatric infectious disease specialist at the University of Arkansas of Medical Sciences in Little Rock.

In the United States, the Centers for Disease Control and Prevention (CDC) recommends that children aged six months to four years wait three to eight weeks Children between the first two doses of the Pfizer vaccine, and children between the ages of six months and five years wait four to eight weeks between the first and second doses of Moderna.

While Canada’s National Advisory Committee on Immunization has recommended an interval of eight weeks for the modern vaccine.

The CDC website notes that, based on studies in adults and adolescents, an interval of up to eight weeks People aged six months to 64 years could help increase in antibody levels You reduce the chance of side effects such as myocarditis and pericarditis.

However, scientists believe the CDC’s view may be exaggerated and highlight the risk that children are not protected during this period, apart from the fact that the study focused on infants. has not been implemented since.

What happens if you lengthen the period between applications of the COVID vaccine dose?

When the vaccine antigen enters the body, immune cells in the blood, known as B cells, begin to Production of antibodies after a few days, Salon Shannon explains that only a few of those antibodies will be able to bind to the virus and prevent it from entering the cell. Nature,

Next, the B cells mutate to improve the ability of their antibodies to fight the virus, a process that takes time. how long before the second dose, better immune system function To recognize the attack and react quickly.


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