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Sunday, December 04, 2022

Emphasize effect of hyperglycemia by perioperative dexamethasone in diabetic patients

The purpose of this study review was to clarify the most appropriate preoperative dose of dexamethasone for diabetic patients.

Diabetes is a disease with a high incidence on the island, as 16% of the Puerto Rican population suffers from it. Photo: Shutterstock.com.

A review study conducted between Puerto Rico and universities in the United States states that the evidence suggests that patients Diabetics receiving dexamethasone in the perioperative period are more likely to develop hyperglycemia blood glucose peak 30 to 45 mg/dL in the first 24 hours after one dose Only.

Its purpose suggests that perioperative administration of a single dose of dexamethasone in this population of patients helps reduce postoperative nausea, vomiting, bloating and pain.

However, he says it is not clear which dose achieves these effects while reducing Hyperglycemic effect on patients with diabetes.

precisely the team decided to study to clarify diet Most appropriate perioperative administration of dexamethasone in patients with diabetes and, if necessary, suspend it in patients with poor glycemic control.

Methodology includes a literature search Using PubMed and the Cochrane Database of Systematic Reviews, which revealed 17 potential sources of evidence. Some eight sources met the inclusion criteria. Sources include a systematic review With meta-analysis, one randomized controlled trial and six observational studies.

One study. described the high level of blood glucose with dosage is increasing, but no other sources have supported this finding. Available studies were markedly heterogeneous in design and proportion of diabetic subjects included, and most were of low quality.

Although the study has its own recommendations on the use of this drug, it also emphasizes that there is insufficient evidence to measure the hyperglycemic effect of commonly used doses of dexamethasone, and that rigorous studies are needed.

literature assumes that Dexamethasone plays an important role in in the control of postoperative nausea and vomiting, as it has shown great efficacy; However, its use in patients with diabetes is cautious, and anesthesiologists have avoided its use because of the increase in plasma glucose.

Dexamethasone is a steroid drug that controls the inflammatory process, as it reappeared during the advent of the COVID-19 pandemic.

According to the country’s endocrinologists, diabetes is a disease with a high incidence on the island, as 16% of the Puerto Rican population suffers from it.

View the study published by the Journal of Perianesthesia Nursing ASPAN here.

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