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Friday, December 02, 2022

Europe follows in America’s footsteps and empowers to divide each dose of monkeypox vaccine by five

The European Medicines Agency (EMA) has given the green signal to the member countries of the European Union to administer small dose of vaccine monkey pox To expand the limited stock of the drug.

The agency’s advice is in line with the so-called fractional dosing approach endorsed by the FDA, the United States pharmaceutical agency, that under this protocol it would be sufficient to use fifth part of the usual dose per person in two punctures, to be effective it must be applied as a intradermal injection, In the end, it will be divide each dose by five from the monkeypox vaccine.

The vaccines, called Geneos, Imvanex, and Imvamune, depending on the geography, were designed to be injected into a layer of fat under the skin, known as: subcutaneous injection,

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as a temporary measureThe EMA has said that national authorities may decide to use the vaccine as an intradermal injection at low doses to protect those at risk during the current monkeypox outbreak, while the supply of the vaccine remains limited.

recommendation a. based on Study involving nearly 500 adults and compared the performance of the intradermal or subcutaneous vaccine in two doses given one month apart.

the one who received intradermal injections Received youone-fifth the subcutaneous doseBut produced the same levels antibodies compared with those who received the original subcutaneous dose, the EMA said.

However, the agency warned that there was a large risk of local reactionssuch as redness and skin thickening or discoloration After intradermal injection.

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Since the beginning of May, more than 40,000 cases Cases of monkeypox – including a handful of deaths – have been reported in more than 80 countries where the virus is not endemic.

The World Health Organization has declared an outbreak global health emergency, Vaccines made by Bavarian Nordic are in short supply.

Many countries are increasing the dosage available to make the most of the existing supply, with unknown results.

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