Sunday, November 27, 2022

Health reports the first two deaths of children from unknown hepatitis, one of them in Madrid. Madrid Gazette

Ministry of Health has reported the first two deaths in Spain due to hepatitis of unknown origin in children after failing to undergo a liver transplant. It is of a 6-year-old boy who died in a hospital in Madrid and a 15-month-old boy who died in Andalusia.

Of the 45 cases detected in Spain as of 2 August, two required liver transplants (a 3-year-old girl and a 6-year-old boy living in Aragon). A 6-year-old boy living in Murcia started having symptoms on 2 July, and on 18 July he was transferred to a hospital in Madrid for a transplant in critical condition (cerebral edema); The transplant was performed on 29 July and he died 24 hours after the transplant.

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As of 3 August, a 15-month-old boy living in Andalusia who was admitted with a positive culture for adenovirus in a serious condition (encephalopathy and severe coagulopathy) with severe gastroenteritis at the end of June. The case required an urgent liver transplant and died within 24 hours. Considering the seriousness of the episode, it has been included in this report as an additional episode of the presented series.

On April 5, 2022, the United Kingdom (UK) notified the WHO of the alert following the detection of 10 cases of severe acute hepatitis of unknown cause in children. The surveillance of this unit in Spain began from that very moment. As of 28 July, 507 cases have been reported in 21 countries in Europe, 273 in the United Kingdom. Cases have been detected outside Europe, particularly in the Americas region (487 cases).

The majority of cases occurred between weeks 12 and 21 (March 21 to May 29), a significant portion of the cases detected in the rest of the world.

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In 2022, as of 3 August in Spain, 46 cases have been notified to the National Epidemiological Surveillance Network, aged between 0 and 16 years, with more than 60% being girls. Cases were detected in 10 autonomous communities, there was no epidemiological relationship between them, and symptoms began between January 2 and July 2, with most occurring between 10 and 17 weeks (March 7 to May 1) .

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