How the bivalent vaccine approved in the UK works

Britain became the first country to approve a bivalent coronavirus vaccine. It generates immunity against both the original version of Covid-19, SARS-CoV-2, and the first omicron version, BA.1.

This type of vaccination is fine-tuned to the growing of the omicron type and its subclasses. In fact, known vaccines have been shown to be less effective with BA.4 and BA.5 of this strain.

The acceptance of the British opened the door to the use of bivalent vaccines. The rapid development of coronavirus variants raises questions about the efficacy of current inoculations.

It is expected to release between September and December. In addition, it is expected to be used initially in people over the age of 50 and in at-risk populations on the island.

How does the bivalent vaccine work?

Within months of the coronavirus pandemic, the scientific community developed and distributed vaccines against SARS-CoV-2 around the world. The response was swift and many countries were allowed to relax health deprivation measures.

However, the massive advancement of new strains reduces the effectiveness of vaccines. Especially with oomicron variants, which have a greater potential for contagion and immunodeficiency, thanks to their modifications in the spike protein.

For this reason the American company Moderna developed the first bivalent vaccine, It attacks both the original coronavirus strain and the latest version, Omicron.

This is the same method used by the well-known influenza vaccine, as multiple strains are also used in the same dose.

Trials on 437 patients indicate that this vaccine is safe and provides greater protection.

What about variants?

This vaccine attacks the main strain of Omicron, thus reducing its effectiveness with sub-lineages, especially those that differ more from the original. Though, of course, it has more immunity power than the existing variants.

It is very likely that in the future we will have combined vaccines that include the original versions, together with those that will appear during the development of the lineage.

Also, if you have existing types, it may mean that immunity lasts longer.

However, the development of new strains will once again present the scientific community with new challenges to defend against the coronavirus.


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