Tuesday, November 30, 2021

J&J: Booster dose of its COVID shot gets overwhelming response

LONDON (AP) – Johnson & Johnson released data showing that a booster dose for a one-shot coronavirus vaccine elicits a stronger immune response months after people get their first dose.

J&J said in a statement Tuesday that it previously conducted two preliminary studies on people who had previously been vaccinated and found that the second dose increased antibody response in adults aged 18 to 55. The results of the study have not yet been reviewed.

“A booster dose of the Johnson & Johnson COVID-19 vaccine further increases antibody responses among study participants who previously received our vaccine,” said Dr. Mathai Maimon, global head of research and development at J&J. The company previously published data showing its one-shot dosage provided protection for up to eight months after vaccination.

J&J said it is now in talks with regulators including the US Food and Drug Administration, the European Medicines Agency and others about using booster doses of its vaccine.

J&J’s vaccine is approved for use in the US across Europe and plans to share at least 200 million doses with the UN-backed COVAX effort aimed at distributing the vaccine to poorer countries. But the company struggled with production problems and had to throw out millions of doses made at a troubled factory in Baltimore.

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The J&J vaccine has been viewed by many health officials as crucial to ending the pandemic because it requires only one shot, but fears about the easily spread delta coronavirus variant have led many governments to choose between multiple approved vaccines. to consider the use of booster shots.

Last week, FDA experts recommended that people aged 65 and over get a third dose of the COVID-19 vaccine made by Pfizer-BioNtech, while Britain’s first for people 50 and over Authorized booster shots, as well as in addition to priority groups such as health workers and underprivileged people. Health Conditions. Other countries, including Israel, France and Germany, have also started giving some people a third dose of the vaccine.

The World Health Organization has urged wealthy countries to stop giving booster doses at least until the end of the year, saying the vaccines should be redirected immediately to Africa, where less than 4% of the population is fully immunized. In a paper published last week in the journal Lancet, top scientists from the WHO and FDA argued that the average person does not need a booster shot and that vaccines authorized to date protect against severe COVID-19, hospitalization and death. Provide strong protection.


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