Wednesday, May 25, 2022

Lower chance of admission for COVID-19 patients with Omicron vs Delta

FRIDAY, May 6, 2022 (HealthDay News) — Patients with severe acute respiratory syndrome coronavirus 2 micron infections are less likely to be hospitalized than those with delta infections, according to a study published in the May issue of Is. e-biomedicine,

Emery Fall, PhD, of the Johns Hopkins School of Medicine in Baltimore, and colleagues conducted a retrospective observational study between the last week of November and the end of December 2021 to examine whether clinical outcomes and viral load Whether or not there are differences between Delta and Omicron. infection during the period when both types were circulating.

The Omicron type displaced deltas during the study period, and by the end of December 2021, it accounted for 95 percent of the circulating lineages. The researchers found that 1,119 patients with Omicron infection were more likely to be vaccinated, but less likely to be admitted, required intensive care unit-level care, or vaccinated status (cycles) compared to 908 patients in Delta. Despite this, he became a victim of infection. threshold values [95 percent confidence intervals]0.33 [0.21 to 0.52]0.38 [0.17 to 0.87]and 0.26 [0.06 to 1.02], respectively). Irrespective of vaccination status, no statistically significant difference was observed in cycle threshold values ​​depending on the lineage. Compared with fully vaccinated patients without boosters and unvaccinated patients, enlarged patients had reduced recovery of infectious virus in cell culture with the delta lineage. However, immunization of patients with Omicron infection did not affect the recovery of infectious virus.

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“Our data suggest that Omicron-infected patients are less likely to develop serious disease than Delta, yet we show that Omicron is associated with greater infections of fully and booster vaccinated individuals, which are associated with immune evasion.” likely to be the cause,” the authors write.

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