A scientific team from the Universities of Granada and Cadiz has found the mechanism that links diabetes to an increased risk of Alzheimer’s, which could represent a “significant discovery” for tackling this type of dementia.
As reported Monday by the Granada Academic Institute, diabetes favors soluble forms of so-called “amyloid beta,” which are particularly toxic and damaging to neuronal tissue.
Scientific discoveries relate this disease to Alzheimer’s, according to the study in which researchers from the University of Cádiz have participated together with professor of the Department of Physiology of the University of Granada Juan José Ramos Rodríguez.
The description of the deposition process of “amyloid beta peptide” in a combined model of Alzheimer’s disease and diabetes provides a new therapeutic target on which to work to slow or stop the development of this dementia, so it is one of the main approaches Will be discovered in future.
Diabetes, a risk factor for dementia
In recent years, diabetes and prediabetes have been recognized as a risk factor for dementia, but the mechanisms mediating this association are not fully known.