It is believed that BMI – Body Mass Index, as it indicates overweight and obesitythey are closely related to the risk of Madness, the higher the BMI, the greater the risk cognitive declineGiven that obesity is often accompanied by various metabolic disorders such as diabetes, These disorders and their association with dementia have led to Alzheimer’s disease being referred to as “type 3 diabetes”.
However, these close relationships would be more complicated that have been seen till date. This is suggested by a new work published in Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association, will be the pattern of weight gain and/or loss Which would have a strong relationship with dementia.
currently Madness one of the biggest public health problems worldwide, which is already affecting 50 million people Worldwide. In fact, it is expected to increase drastically in prevalence and eventually affect over 150 million people for the year 2050.
[Los ‘siete mandamientos’ diarios para evitar perder la memoria y sufrir demencia según la ciencia]
For its part, obesity, most commonly diagnosed by BMI, also remains a global problem. Several studies have suggested that obesity in middle age The risk of dementia will increase in the medium and long term, However, the association between BMI and dementia risk is unclear.
Now, researchers from Peking Union College of Medicine as well as Boston University Chobanian and Avedisian Schools of Medicine and the Chinese Academy of Medical Sciences have discovered that there may be a link between the two. different patterns of change lifetime BMI and ultimate risk of dementia,
As Dr. Rhoda Au, lead author of the study and professor of anatomy and neurobiology, recalls, this study is unique because until now Pattern of weight gain/stability/loss, but the total BMI without more. Apart from this, it is also measured on many occasions. Only once In studies lasting several years.
But it is important to take into account variations throughout life, and can give us data over the medium and long term. In this case, thanks to the Framingham Heart Study, a group of participants was followed for 39 years and their weight was measured every 2-4 years. pattern compared stability, weight gain and lossand took into account No later diagnosis or dementia long term.
According to the study, the general trend of Decrease BMI was associated with a increased risk of developing dementia, However, on specific review, a subgroup was discovered with a pattern decrease after initial increase of BMI, both occur within middle age.
This pattern would be necessary for an association between decreased BMI and dementia. According to the AU, a steady increase in weight is common as you age, but it The fact that unexpected weight loss after middle age will be a warning sign For which the primary care physician should be consulted to conduct necessary preventive studies.
Potential treatments are currently being tested that can be started if the risk of dementia is detected early, although most of them are still under study and are pending availability and approval.
Nevertheless, the researchers hope that this study will be the first step in many others focused on the prevention, control and treatment of dementia. “No is inevitableAnd monitoring risk indicators, as easily as monitoring weight patterns, may provide opportunities for early intervention that may change the trajectory of disease onset and progression,” the researchers concluded.