Monday, March 20, 2023

Oral azithromycin is an effective antimicrobial against uncomplicated intestinal fever.

Outpatient treatment allowed patients to receive fewer antimicrobials and there were no complications.

The total duration of antibiotic in hospitalized patients was 7 days versus 11 days. Photo: Shutterstock.

fever Enteric, or typhoid fever, caused by the bacterium ‘Salmonella typhi’, is currently rare in developed countries, with health sectors that know how to manage the disease; but it’s still serious public health threatIn those countries with health systems Developing, with a higher prevalence in children, according to MayoClinic.

This bacteria is present in contaminated food and water, causing typhoid fever when in close contact with an infected person. Oral Azithromycin Treats Safely fever Complicated imported enteritis in outpatients.

and it should be considered remedy For patients outpatient with azithromycin With confirmed uncomplicated typhoid, it was possible to confirm through this retrospective descriptive study that the use of this antimicrobial in non-endemic environments is safe and effective compared to hospital treatment.

This study is carried out with a retrospective analysis of all patients with confirmed typhoid fever between August 2009 and September 2020. Demographic, clinical, laboratory and microbiological data were collected and compared between the inpatient and outpatient populations, along with the results of the investigations. Those who had complicated typhoid fever. , treatment failure and relapse.

A total of 93 cases of enteric fever, confirmed by culture; 53% (n=49) were managed on an outpatient basis; 59% (n=55) were male patient, The mean age was 31 years, and one (interquartile range, 26–39) years.

Presenting Symptoms:

On the other hand, 94% (n=87) patients had treatment data (43 inpatients, 44 outpatients), meaning that 84% of outpatients versus 13% of inpatients received intravenous ceftriaxone (p < 0.01); 70% of outpatients versus 11% of inpatients received azithromycin (p < 0.01).

57% outpatient versus 19% inpatient (p < 0.01) prescribed antibiotic treatment.

The overall duration of antibiotic in hospitalized patients was 7 days versus 11 days (p < 0.01), 66% (n = 29/44) of patients were hospitalized at first presentation and 98% (n = 43/24). 44) were hospitalized for at least 3 days, and with a median admission of 4 days.

On the other hand, treatment failure occurred, versus one outpatient being switched (day 7) to amoxicillin; Two outpatients received long courses (14 days) of oral azithromycin (one persistent fever on day 6, one persistent bacteremia on day 6); Both got well.

Three azithromycin-resistant outpatients switched to intravenous ceftriaxone, then to ciprofloxacin/amoxicillin/ceftriaxone.

Keep in mind that if you think you may have typhoid fever, see a doctor right away. . Special doctors to take care of you.

Nation World News Desk
Nation World News Desk
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