Wednesday, November 30, 2022

Pediatricians ask “peace” about acute hepatitis in children: “There are no more cases than before”

“peace”. This is the message that experts sent after learning that the Valencian community has registered itself First case of severe hepatitis in children of unknown origin Following the alert launched in April by United Kingdom Detection of abnormal growth in this type of case.

Since then till today and the entire health system is paying special attention to it. all in spain they have registered 48 cases so far in children with an average age of five years. One from the Valencian Community was registered early august And, as confirmed yesterday by Health Minister Miguel Minguez, it is a two years old That he is already at home, discharged and has developed favorably.

Fear is of a parent, because it is hepatitis (inflammation of the liver) that has nothing to do with the virus that usually causes it or with any toxins yes it’s poorly developed In three of these 48 cases: three children required a liver transplant and two of these children died within 24 hours.

“Same cases without UK alert”

Despite this, experts call for calm because “There are no more cases of hepatitis There are no more pediatric liver transplants in children of unknown origin and in Spain, as would have happened without the UK alert,” he explains. louis blesaValencian Pediatrician and Current President of the Spanish Association of Pediatrics, AEP.

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According to the expert these 48 cases do not represent an irregularity With people who had registered since January without alerts activated. “Without the warnings from the United Kingdom, we would have had the same number of hepatitis of unknown origin in children and the same number of transplants. There is not a plethora of cases,” he explained.

Children’s rooms at the Hospital La Fe de Valencia. Fernando Bustamante

And that, according to Blassa, it’s common for severe hepatitis to be recorded in children “who don’t get to be associated” and in those who don’t. So many common viruses are ruled out those that cause them, “hepatitis A, E and other viruses that are usually behind such as herpes zoster or Epstein-Barr but which are not positive for toxic such as food or medicine, or metabolic problems. no clear relationship“, Understand.

The latest report from the Ministry of Health on this health alert testifies to: no additional cases Neither the deviation due to this nor the number of children admitted to the hospital liver transplant that they are made. so far this year they have done Four pediatrics across Spain Due to sudden liver failure but only three would adapt to the alert. There were 8 in all of 2021, the same as in 2020.

Blassa: “In the United Kingdom they have seen an association with an adenovirus, but they also believe that there are other factors, genetic as well”


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An adenovirus, the prime suspect

severe acute hepatitis unknown reason It continues to be reported as such because, while ruling out the usual suspects, medical teams still haven’t found what caused them. The main hypothesis that the scientific community now has after studies (especially) from the United Kingdom is that there is a previous infection with a kind adenovirus (A group of viruses that commonly cause respiratory diseases). According to the Ministry of Health, this association has been “Very important” in UK affairs Where they come to the conclusion that there must be other “cofactors” that will exert this effect.

“In the United Kingdom, where they have seen a plethora of cases, they have seen this association with an adenovirus, but they also believe that there are other factors leading to this infection that are somewhat more serious, for example Other viral infections and a particular genetic predisposition that you wouldn’t have here,” Blassa explains.

Regarding the role that COVID-19 may have played (and which was also considered as a trigger), the expert assured that no link has been observed, however. yes the pandemic has affected“Why are children who have not been exposed For many viruses such as adenoviruses that somehow train the body to be prepared and may have a poor immune response but in no case have an association with vaccines, for example”.

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