Wednesday, January 26, 2022

Preliminary research suggests Omicron has more asymptomatic carriers than earlier variants – National | Globalnews.ca

Preliminary findings from two clinical trials in South Africa suggest that the Omicron coronavirus variant has a much higher rate of “asymptomatic carriage” than the earlier variant, which may explain why it has spread so rapidly around the world .

The study – one of which was conducted last month at a time when Omicron infections were on the rise in South Africa and another that retested participants around the same time – found that a much higher number of people had tested positive for the coronavirus. , but were not showing symptoms as compared to previous tests. ,

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In the Ubuntu study evaluating the efficacy of Moderna’s COVID-19 vaccine in people living with HIV, 31 percent of 230 participants who underwent screening tested positive, with all 56 samples available for sequencing analysis as omicrons. Verified in.

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“This is in stark contrast to the pre-omicron positivity rate, which ranged from less than one percent to 2.4 percent,” the researchers said in a statement.

In a subgroup of the Sissonke trial evaluating the efficacy of Johnson & Johnson’s COVID-19 vaccine, the average asymptomatic carriage rate increased from 2.6 percent during the beta and delta outbreaks to 16 percent during the Omicron period.


Click to play video: 'COVID-19 hospitalizations key statistic during Omicron outbreak'







COVID-19 hospitalizations the key statistic during the Omicron outbreak


COVID-19 hospitalizations the key statistic during the Omicron outbreak

The researchers said, “Sisonke’s study involved 577 subjects who had been previously vaccinated, …

He added that “the high asymptomatic carriage rate is potentially a major factor in the rapid and widespread spread of the variant, even among populations with high prior rates of coronavirus infection”.

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South Africa experienced a surge in COVID-19 infections since late November, around the time its scientists alerted the world to Omicron. But new cases have dwindled and there are early signs that the wave has been marked by less severe disease than previously thought.

(Reporting by Alexander Winning, Editing by Ed Osmond)

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