A research team from the Complexity Science Hub and the Medical University of Vienna (Austria) analyzed 180,034 patients with diabetes and found evidence that women are at higher risk of VTE than men, especially during perimenopause. Overall, a huge amount of study has been done…
A research team from the Complexity Science Hub and the Medical University of Vienna (Austria) analyzed 180,034 patients with diabetes and found evidence that women are at higher risk of VTE than men, especially during perimenopause.
In total, data from approximately 45 million hospitalizations and 7,239,710 patients were studied in Austria between 2003 and 2014.
,Our analyzes show for the first time that diabetes mellitus may be associated with venous thromboembolism (VTE) to a greater extent in women than in men.“, explained elma derwickDell Complexity Science Hub.
Women with diabetes mellitus (DM) also have a 1.52 times higher risk of developing VTE than women without DM. On the other hand, the risk for men is only 1.3 times higher.
,From the age of 40, in particular, the relative risk of VTE increases“, Understand carola deschinger, one of the authors. According to the results of the study published in the scientific journal Diabetes Research and Clinical Practice, the effect is greater in women between the ages of 50 and 59, where the risk is 1.65 times greater.
To determine the gender-specific effect of diabetes mellitus on VTE risk, the team examined a population-based data set. With approximately 45 million data records, it covers all hospital stays in Austria between 2003 and 2014. Of the 180,034 DM patients, 70,739 were female and 109,295 were male.
Venous thromboembolism (VTE) includes two clinical conditions: deep vein thrombosis and pulmonary artery embolism, the latter being a dangerous complication of thrombosis. In general, the risk of developing venous thromboembolism is more or less the same in both sexes.
Diabetes mellitus, a chronic disease affecting more than eight percent of the world’s population, is known to be a risk factor for VTE. ,In our study, we again found a 1.4-fold higher risk of VTE in patients with diabetes mellitus than in the control group without diabetes mellitus.Derwick says.
Novelty has a gender aspect. While conventional treatment methods can hardly account for gender-specific differences in many diseases,”Today we already know a lot about it, thanks to great research efforts and Big Data analytics.Derwick says.
As a result, these differences can be analyzed in detail and treatments can be adjusted accordingly. This study was preceded by two other studies that addressed gender-specific differences of patients with diabetes in the expression of depression, on the one hand, and Parkinson’s disease, on the other. In this case, a significant difference was also observed on the basis of gender.