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Friday, December 02, 2022

Study points to skin-to-skin contact as most likely cause of monkeypox transmission

Dermatology Service of 12 de Octubre University Hospital in Madrid participated in a prospective observational study indicating that skin-to-skin contact is the most likely cause of monkey virus transmission in 181 patients from Madrid and Barcelona.

According to a statement from the Community of Madrid, research published in the journal ‘The Lancet’ also indicates that infection May present with unusual manifestations Not yet described, therefore it urges healthcare professionals to be attentive to this condition, especially important in the diagnosis of pathology.

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study in which German Trias and Val d’Hebron HospitalNear Foundation fight against infection, was based on a detailed analysis of clinical epidemiology and characteristics of 181 confirmed cases, of whom 175 were male (98%) with a mean age of 37 years. As for the lesions, all had skin manifestations, with the number of lesions described so far being as low as 3 to 20.

Of the 181 cases, 108 contributed by the Hospital 12 d’Octubre, only three required admission because of complications. refering to The average duration of the incubation period was only 7 days.According to the researchers, a shorter period that should be taken into account to assess the timing of vaccination of high-risk groups, as pre-vaccination may be more effective than post-exposure vaccination.

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Based on evidence of skin-to-skin contact during sexual intercourse as the main route of transmission of monkeypox, the findings of this study provide essential information to reach an accurate diagnosis, such as the fact that the pattern of transmission on changed. opportunity from respiratory contact to skin contactwith the appearance of unusual manifestations.

Additionally, research indicates that Viral loads were surprisingly high in samples from skin lesions Compared to that obtained from the pharynx, which needs to be further studied and based on the findings, whether or not to opt for home isolation of those affected by respiratory reasons.

abnormal manifestations of disease

All cases explained feeling sick before or after the rashBut some unusual symptoms also appeared, such as proctitis in 25% of cases, tonsillitis in 11%, and abscesses in 3%.

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In particular, they draw attention to the proctitis that has been presented in many of the cases studied, as they had systemic manifestations before the appearance of skin lesions and even before tonsillar ulceration.

In a prospective analysis of all patients, not only the sexual behavior and the form of presentation of the infection were analyzed, but theirStudied results of e-examinations and clinical follow-up and tests Viral tests were performed on samples obtained from wounds on the skin, throat and anal mucosa.

Thanks to this, the research confirms the symptoms of other retrospective studies, but at the same time, given the large volume of samples and the detailed clinical analysis of cases, it adds new symptoms that have not yet been described, such as Proctitis and ulceration of the tonsils

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