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Sunday, December 04, 2022

They link blood type to risk of having a stroke before 60: this is the most prone group.

Genetic variants linked to a person’s blood type may be related to their risk of early stroke, according to a new meta-analysis published online in Neurology, the medical journal of the American Academy of Neurology.

The meta-analysis included all available data from genetic studies involving ischemic stroke in young adults with a . Due to this Blockage of blood flow to the brain.

“Genetic variants associated with blood types A and O are almost all genetically linked to early stroke”

“Non-O blood types have been previously associated with early stroke risk, but the results of our meta-analysis show a stronger association between these blood types with early stroke than with late stroke, and blood type A in particular.” In linking risk with , “study author Braxton D., of the University of Maryland School of Medicine in the United States. Michelle explains. In particular, our meta-analysis shows that Genetic variants linked to blood types A and O are nearly all genetically linked to early stroke -add-. People with these genetic variants may be more likely to develop blood clots, which can lead to stroke.”

The meta-analysis included a review of 48 studies on genetics and ischemic stroke from North America, Europe and Asia. The study included 16,927 people with stroke and 576,353 people who did not have a stroke. Of those who had a stroke, 5,825 had an early-onset stroke and 9,269 had a late-onset stroke. Early-onset stroke was defined as ischemic stroke occurring before the age of 60 years, and late-onset stroke as occurring more than 60 years of age.

The researchers examined all of the chromosomes to identify genetic variants associated with stroke. They found a link between early stroke and the part of the chromosome that contains the gene that determines blood types A, AB, B and O. They then divided the participants into blood types A, AB, B and O. They compared the prevalence of these blood types among people with early stroke, late stroke, and people who had not had a stroke.

They found that people with early stroke were more likely to have type A blood and less likely to have type O blood. compared to people with late stroke and those without stroke. Both people who had an early stroke and those who had a late stroke were also more likely to have type B blood than controls.

People of European descent were screened and compared 5,825 people with early stroke with 29,320 people who did not have a stroke, the meta-analysis found. 48% of people with an early stroke had a blood type A, compared with 45% of people with a late stroke and 44% of those without a stroke. He also discovered that 35% of people with early stroke have blood group O. wascompared to 39% of people with a late stroke and 41% of those without a stroke.

People with O blood had a 12% lower risk of having a stroke than people with other blood types

After adjusting for gender and other factors, the researchers found that People with type A blood had a 16% increased risk of having an early stroke compared to people with other blood types. People with O blood had a 12% lower risk of having a stroke than people with other blood types.

“This work deepens our understanding of development and changes in early stroke,” said Jennifer Juhl Mazersik, MD, of the University of Utah and a member of the American Academy of Neurology. future research. This is needed to help develop a more accurate understanding of how stroke develops. This could lead to specific preventive treatments for early stroke, leading to less disability during the most productive years of women’s lives. People”.

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