During these more than two years of the pandemic, it has been observed that Children have lower rates of infection by COVID-19 than adults And the symptoms of this population group are also mild. Although the reasons are still unknown, a recent investigation by the University of Queensland (Australia) has found a key to shed light on this fact.
Researchers have found that baby nose lining It is more effective in preventing SARS-CoV-2 infection than it is in adults. This may be one reason why children’s immune responses have so far been shown to be more effective in preventing and fighting COVID-19.
This is why kids fight covid better
“Children have lower COVID-19 infection rates and milder symptoms than adults, but the causes are unknown. We have shown that Children’s nasal linings have greater proinflammatory response to parental SARS-CoV-2 Compared to the nose of adults. But we found that the game is different when it comes to the Omicron version”, the work leader said,
The research team uncovered cell samples from the lining of the nose.e 23 children and 15 healthy adults SARS-CoV-2, The results showed that the virus replicated less efficiently in the children’s nasal cells, as well as a greater antiviral response.
There are several theories about this: “It could be An adaptation to increased threats from ‘foreign invaders’ such as viruses or bacteria seen in childhood, It is also possible that increased exposure to these hazards in childhood ‘trains’ the lining of children’s noses to mount a stronger pro-inflammatory response. either metabolic differences between children and adults could change the way virus-fighting genes are expressed.”
Less effective against Omicron
researchers found that The delta version had much less chance of copying in the cells of the nose of children than in adults. But in Omicron’s case the trend was far less pronounced.
“Taken together, it shows that Children’s nasal lining supports fewer infections and replications from the ancestral SARS-CoV-2, but this may change as the virus evolves,” says says, whose work is published in the scientific journal PLOS Biology.
The researcher believes that “future clinical studies will be necessary to validate these preliminary results in a larger population and” To determine the role of other factorssuch as antibodies, in protecting children from SARS-CoV-2 infection”.