Friday, January 27, 2023

UNAM discovers molecule that could fight obesity

Researchers from the National Autonomous University of Mexico (UNAM) discover molecule can help deal with high rates of obesity In the country, it will also serve to reduce the risk of suffering from diabetes.

According to the Mexican Social Security Institute (IMSS) 4 out of 10 people suffer from it obesityWhich in turn predisposes to the development of other diseases like diabetes.

Discovery by Juan Miranda Rios of the Institute for Biomedical Research (IIBO) UNAMshow that the discovery of molecules Ribonucleic acids (RNAs) participate in the regulation of the metabolism of various sugars.

“By knowing the functions of RNA we can, in the long run, attack complex problems such as obesity, diabetes and cancer,” explained Juan Miranda Rios.

Currently, models of obesity in the worm Caenorhabditis elegans, to see how different diets (high in sugar and fat) modify molecule. This sample is used because the genes that code for proteins and RNA are very similar to those in humans.

gained knowledge about molecules RNA and as a result of the development of technology over the years, there may be a special treatment against obesity Over the next 10 years, as resources and research are needed to get all of the clinical trials validating this treatment.

Study of RNA molecule will help fight cancer

Juan Miranda Ríos explained that the study of these molecules has a positive impact on human health, since some diseases may originate from failure to produce certain RNAs or small proteins.

for researchers UNAM It is essential to know how these small RNAs and their proteins work, to initiate the design of therapeutic strategies that allow to upregulate their function and improve human health.

UNAM Gazette

“It is important to recognize that studying these RNAs is leading us to understand some disease mechanisms. By thinking that some of these genes would produce proteins, it turned out that many diseases were not previously attributed to faulty genes. We now know that there are genes that produce RNA that, if not produced in the right amounts, can cause diseases,” commented Juan Ríos.

The team, led by UNAM researchers led by Juan Miranda Ríos, is currently reviewing the expression of these small RNA molecules in order to design strategies to eliminate their function and reduce changes in cancer cells.

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