Thursday, June 8, 2023

We cannot rule over pandemics

The risk of a pandemic, which could generate a greater crisis than the one that generated Covid19 in the world, the Mexican health systems must strengthen preventive measures, investing in the development of vaccines, treatments and new technologies.

In Jalisco, one of the challenges in the face of the confluence of febrile diseases, which are mainly endemic such as influenza and dengue with some temporary movements, coupled with Covid19, is important to strengthen the molecular diagnostic infrastructure as triangular units to perform tests. they offer specialized workshops, clinical studies and treatments for each disease.

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But a big challenge stood out in the conversation Western infectologist Jaime Briseño Ramírez, internist at the internal medicine service of the old Civil Hospital of Guadalajara “Fray Antonio Alcalde” and director of the Health Division of the University Center of Tlajomulco (CUTlajomulco) of the University of Guadalajara (UdeG); transfer it to public communities and improve prognosis. It meant that one of the problems humanity faces is to act too late, without being prepared to face and reduce the dangers in the face of future epidemics.

What is our approach to future pandemics?

“Since humanity is more prone to expect diseases that generate zoonotic jumps, favor the flow of research to increase, in particular to explore delivery methods, vaccines, diagnostic methods and develop therapeutic strategies, such as antiviral drugs, among others; If history has taught us something and it has taught us several times, great “Pandemics arise from zoonotic movements. In this scenario, as a society, we must be proactive, to invest resources, there is talent everywhere in the world.”

What will be the result?

“In the examples of SarsCov2, Mpox, dengue and Ebola, it usually occurs with an epidemic outbreak or that can have a pandemic potential, so we are doing it, we have known since 2002 that zoonotic diseases that generate wildfires can have a pandemic potential that we saw with Sars. And it happened until 2012 where The market appeared again; 2009 where h1n1 influenza appeared and recently Covid 19 at the end of 2019 and the beginning of 2020, and we see it again with some isolated cases of avian influenza.

What we have seen so far and Covid19 is a clear example of this, that the world reacts when a disease of this type generates significant consequences in the first countries of the world, such as the United States of America or the European Union, we have diseases that have afflicted us chronically. not everything is always invested in the research of these, such as tuberculosis, malaria and itself is denied, if the problem is not understood from a global point of view and knowing that in some countries there is hardly any support in the future. which has pandemic potential, we will have to generate strategies in this category.

Is it a network check?

“There are some lines that have been made after Covid19 and must be made, for example with the creation of the World Health Organization, the guidelines on which resources are to be distributed, in which groups of diseases, the most of which are included: coronavirus, influenza, . Ebola, Marburg virus disease, Crimean fever, fever Congo, the Nipah virus, among others.

On the other hand, there are ports of intelligence, epidemics and pandemics that have been established, for example one WHO established them in Berlin, the other of them is in a joint effort between the United States and the United States, but there are features of what should be a Global Intelligence Network that allows to follow , to follow and invest in the generation of vaccines or future medicinal plans.

What’s next?

“This is the format for which we are migrating, because the pandemic is a global problem to be understood, the classic example was when there were vaccines for Covid, where the vaccines that were distributed with the best profile, I call vaccines. Messenger RNAs were distributed in the first regions of the world and we had a queue in many countries, Mexico was a central place in that context, but we had to try to access the vaccine in many countries.

While Mexico has started its vaccination program, many Asian, Central and South American countries have not started a vaccination plan, which speaks of equity in the global health system and what has happened? that affected us all, because when in India, South Africa, in Brazil, when the pandemic came, new variants were generated and those variants were redistributed all over the world and this is like a boomerang if you just have your population and you don’t pay attention to what’s going on it can happen in distant countries and in this case we are talking about one virus, which was SarsCov2, when we did not pay attention to prevention or treatment strategies, new variants arose that later affected your population and this is it. boomerang from which we have not yet been able to get out.”

What is the challenge?

“Covid19 is a clear example that I did nothing for 15 years, we had the same Mpox outbreak from 1970 in Central and Sub-Saharan Africa, which was the vaccine for smallpox, when it was eradicated, caused Research to drop to the rough and at this moment we have nothing more than therapy which is tecovirimat, the vaccine that is not for Mpox is for smallpox An example that could be catastrophic in the future is avian influenza.

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