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Wednesday, November 30, 2022

Why the future of ‘in vitro’ fertilization passes through Spain: the secrets of TMRW, backed by the co-founder of PayPal or the CEO of YouTube

You can find many luxury stores from Burberry to Breitling as you walk down Oxford Street in London.

Europe’s busiest shopping street is visited by half a million people a day, many of whom specifically come to shop on its premises.

In this same location, the Peter Thiel-backed startup plans to start a revolution in the European egg freezing market.

TMRW Life SciencesFounded 4 years ago in New York, has developed a platform that Automates the process of storing and freezing eggs and embryos used in fertilization processes in vitro (FIV).

The company, which is making investments including YouTube CEO Susan Wojcicki and Google Ventures among others, has raised $153.5 million so far. TMRW is part of the breeding sector, which is booming, raising $823.1 million from venture capital firms in 2021, an annual increase of 33%, according to data from pitch book,

Inside its London headquarters you won’t see typical office tables, as employees often work around a giant machine with a retina scanner that is in the center of the room.

it’s about Latest Technology of TMRWwhich has not yet been commercialized.

The company uses its robotic technology and digital tracking system to help partner clinics Store and manage frozen eggs more efficiently, It also allows them to digitize the records of these eggs so that they don’t need to be tracked manually, a strangely archaic process to which many clinics still cling.

Cynthia Hudson, an embryologist with more than 20 years of experience, is vice president of clinical strategy for TMRW. It recently demonstrated a frozen egg storage process at its London headquarters, making it possible to see how its latest technology works.

Because the demonstration took place in the office and not the clinic, no actual eggs or embryos were used.

The Storage Container In Which The Frozen Suppository Bottle Is Located.

After removing the ovules, embryologists evaluate which ones are “mature,” that is, they have the potential to be fertilized, and prepare them to freeze, The suppository is placed in a vial that is marked for identification. The vial is then registered in the system.

Tmrw

Its patented technology digitally identifies and tracks stored eggs so that they can be controlled remotely.

TMRW uses Radio Frequency Identification (RFID) So clinics can track samples accurately and prevent mixing.

Tmrw

The company also maintains a digital record of patients’ eggs (rather than a handwritten label), which is linked to a barcode placed on the vial.

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As more and more young LGBTQ women and couples turn to alternative ways to start a family, egg freezing and IVF procedures are In the UK there has been a 10-fold increase in the last decade, TMRW hopes to build on this momentum to introduce its proprietary technology to a wider demographic in the UK market.

Fake Photo Of A Patient'S Archived Egg Registry.

Next to the office were some huge tanks of liquid nitrogen. Frozen eggs and embryos have to be stored -196 degree centigrade. Feather To be able to be “preserved indefinitely” almost.

Tmrw

In fertility clinics, eggs are immersed in liquid nitrogen in a process called vitrification, after which they can be stored using TMRW technology. This “quick freezing” technique reduces the chance that the water inside the ovule will crystallize.

The freezing and thawing process is delicateAnd let’s not forget the risks involved in investing in this process.

In the UK, the procedure can cost up to £8,000 (over €9,000) per cycle and is described as painful and invasive, according to The Human Fertilization and Embryology, one in only 22% of treatments in 2019. successful conception rate. Authority (HFEA).

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On the other hand, the egg freezing process in Spain Can be had for between about 3,000 and 4,000 eurosHowever it should be kept in mind that this is not the same technology that TMRW uses.

While the United Kingdom’s National Health Service (NHS) does not cover the cost of egg freezing as long as the patient is undergoing medical treatment that affects her fertility, in Spain this procedure is done through Social Security. It is possible to accomplish.

Tmrw Technique For Egg Freezing

In TMRW, the traditional process of tracking and retrieving eggs by hand has been replaced, and a robotic arm machine Responsible for transporting vials to cold storage units,

The use of robotics is intended to reduce the loss of eggs and embryos, something that has become more prevalent in a manual process that requires scientists to open frozen sample storage tanks by hand to check nitrogen levels , which inevitably creates temperature fluctuations.

Its Patented Technology Digitally Identifies And Tracks Stored Eggs So That They Can Be Monitored Remotely.

The technology at the UK headquarters includes a webcam so that embryologists at TMRW’s New York office can remotely monitor the procedures.

your monitoring system Also conducts wellness checks on the status of the fertility cell and notifies clinics of any problems that arise.

Tmrw Technique For Egg Freezing
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The temperature at which eggs are stored is also continuously indicated, so the embryologist does not need to constantly monitor the level of liquid nitrogen.

Tmrw Technique For Egg Freezing

extension in times of crisis

Although TMRW plans to expand its services to Europe this year with the opening of its first office in London, it is not untouched by the effects of the global tech slowdown. In May, he fired about twenty employees. business Insider,

As part of its foray into London, it will also have to deal with regulatory challenges it did not initially face in the United States. However, it is not clear how the reversal of Roe versus Wade will affect fertilization techniques. in vitro In the North American country, as bioethics experts are concerned the law makes it difficult for fertility clinics to discard frozen embryos.

TMRW CEO Tara Comonte says the company had decided not to expand into China because of the “tough” regulatory and business path that existed there.

Even then, Europe seems to have found an economic stimulus,

“In the United States, the cost of storing eggs averages $70 per month. In the United Kingdom, it is $24 per month, and in Spain it is estimated to be around $30,” he says.

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Germany prohibits the long-term storage of embryos under most circumstances. Comante found that France was the country with the best access to egg freezing treatments, but it was not as attractive because the treatments are subsidized by the government.

This year, the UK government Increase in storage limit for frozen eggs from a maximum of 10 years to 55. Has been doneAnd TMRW sees this as a banking opportunity.

The company recently revamped its storage model, which it plans to launch in the coming months. Here’s a first look at new technology, including a retina scanner for opening containers with advanced security features.

Tmrw'S Latest Technology.

In the coming years, TMRW hopes to expand across the continent, setting up shop in London.

“We have 28 signed clinics. Forecast to start commercially in the United Kingdom, and we will try to continue in Spain And then in Asia,” Comonte says.

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