Monday, December 05, 2022

Your double exists and you probably share DNA with him: A photographic work that sparked science interest

Charlie Chasson and Michael Malone met in Atlanta in 1997, when Malone guest-starred in Chassen’s band. They quickly became friends, but they didn’t notice what others around them saw: Two men can pass for twins.

Malone and Chassen are gets doubled double. They look a lot alike, but they are not related. Your immediate ancestors also don’t come from the same part of the world; Chassen’s ancestors come from Lithuania and Scotland, while Malone’s parents are from the Dominican Republic and the Bahamas.

The two friends, along with hundreds of other unrelated lookalike, found a . participated in François Brunelle Photographic Project, a Canadian artist. The series of photographs, “I am not a stunt double!”, was inspired by Brunel’s search for his own stunt double, the English actor. Rowan Atkinson.

The project has been successful in social networks and other areas of the Internet, but it has also attracted public attention. Scientist Those who study genetic relationships. Dr Manel Esteller, a researcher at the Josep Carreras Leukemia Research Institute in Barcelona, ​​had previously studied the anatomical differences between identical twins and wanted to examine the contrast: People who look alike but are not related. “What is the explanation of these people?” He asked.

Garrett Levenbrück And Roniel Tesler Are Part Of The Doppelgnger Project, With Photographs By François Brunelle, That Sparked Science Interest.

Garrett Levenbrück and Roniel Tesler are part of the Doppelgnger project, with photographs by François Brunelle, that sparked science interest.

In a study published Tuesday in the journal Cell Reports, Esteller and his team recruited 32 pairs of similar-looking people from Brunel’s photographs. DNA study and answer questions about their lifestyle. The researchers used a facial recognition software To measure the similarities between the faces of the participants. Sixteen of those 32 pairs had a total score of identical twins analyzed by the same software. The researchers then compared the DNA of those 16 pairs of doppelgngers to see if their DNA was similar to that of their faces.

Esteller found 16 couples who were “really” alike Shared significantly more genes than the other 16 pairs That software is considered less uniform. “These guys really look alike because they share important parts of the genome, or DNA sequences,” he said. People who look alike have more genes in common” would seem like common sense, but never proven”Told.

However, DNA alone doesn’t tell everything about our makeup. The experiences lived by us and our ancestors influence the activation or deactivation of genes, which scientists call the epigenome. And our microbiome, a microscopic co-pilot made up of bacteria, fungi and viruses, is also influenced by our environment. Esteller found that while the couple’s genomes were similar, their epigenome and microbiome were different. “Genetics unites them, and epigenetics and the microbiome separate them”Told.

Charlie Chasson And Michael Malone Are Part Of The Doppelgnger Project, François Brunel'S Photographs That Inspired Scientific Research.

Charlie Chasson and Michael Malone are part of the Doppelgnger Project, François Brunel’s photographs that inspired scientific research.

This discrepancy tells us that the pairs have a similar appearance. more to do with their DNA than with the environment they grew up in, This surprised Esteller, which expected to see a greater impact from the environment.

Since the form of doppelgngers is more attributable to shared genes than shared life experiences, this means that, to some extent, their similarities are simply Coincidentally, in favor of population growth. After all, there are only a few ways to make a face.

“There are so many people in the world now that the system repeats itself,” Esteller says. “It’s not unreasonable to assume that you are too” Maybe you have a similar look.”

Ana María Sánchez And Catherine Romero Are Part Of The Doppelgnger Project, François Brunel'S Photographs That Sparked A Scientific Investigation.

Ana María Sánchez and Catherine Romero are part of the Doppelgnger project, François Brunel’s photographs that sparked a scientific investigation.

Esteller hopes the study results will help doctors diagnose diseases in the future: If people have enough similar genes to look the same, they can Some even share disease tendencies.

“When it comes to genetics there seems to be something very strong that makes two individuals who look alike have similar profiles in the genome,” said Olivier Element, director of the England Institute for Precision Medicine at Weill Cornell Medicine in New York. who was not involved in the study. Discrepancies between DNA predictions and the actual appearance of people He said they can alert doctors to any problems.

Esteller also said that there may be links between facial features and behavior patterns, and the study results could one day help by providing forensic science A sketch of a suspect’s face in a crime known only from DNA samples. However, Daphne Martashenko, a postdoctoral researcher at the Stanford Center for Biomedical Ethics who was not involved in the study, urged caution in applying these findings to forensic science.

“We’ve already seen many examples of how existing facial algorithms have been used to reinforce racial bias in things like housing, staffing and criminal profiling,” Martashenko said, the study said. “Raises several important ethical considerations.”

Karen Chu And Ashley Wong Are Part Of The Culver City, Doppelgnger Project, Which Features Photographs By François Brunelle, Which Inspired The Scientific Research.

Karen Chu and Ashley Wong are part of the Culver City, doppelgnger project, which features photographs by François Brunelle, which inspired the scientific research.

Despite the potential risks of linking people’s appearance to their DNA or behavior, Malone and Chesson said similar-looking project and knowledge We can all have a secret twinYes, it is a means of bringing people together. The two are still friends after 25 years; When Chassen got married last week, Malone was the first person he called. Although not all people with similar DNA share that bond, Malone said he saw Brunel’s photography project as “another way to connect all of us in the human race.”

new York Times

Translation: Alyssa Cornelli

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